Table 1.
Baseline characteristics by quartiles of FGF23
| Variablea | Full cohort | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 |
|---|---|---|---|---|---|
| N | 47 | 9 | 12 | 14 | 12 |
| iFGF23 (pg/ml) | 32–361 | 363–1074 | 1195–3195 | 3926–22,369 | |
| Age (yr) | 61 (±20) | 66 (±22) | 57 (±18) | 55 (±18) | 68 (±21) |
| Weight (kg) | 68 (±18) | 61 (±16) | 80 (±18) | 66 (±19) | 63 (±12) |
| Male (%) | 70 | 67 | 75 | 64 | 75 |
| EF ≥ 50%, n (%) | 29 (62) | 5 (56) | 9 (75) | 10 (71) | 5 (42) |
| LV hypertrophyb n (%) | 25 (53) | 4 (44) | 5 (42) | 6 (43) | 10 (83) |
| TR jet velocity (cm/s) | 2.6 (±0.5) | 2.5 (±0.7) | 2.3 (±0.3) | 2.7 (±0.3) | 2.9 (±0.3) |
| E to A ratioc | 1.4 (±0.5) | 0.9 (±0.4) | 1.1 (±0.6) | 1.5 (±0.6) | 2.1 (±0.4) |
| LA volume (ml) | 58 (±27) | 56 (±24) | 55 (±25) | 55 (±21) | 65 (±37) |
| Hemoglobin (g/dl) | 11.7 (±1.4) | 11.4 (±1.0) | 11.4 (±1.0) | 12.2 (±1.5) | 11.5 (±1.7) |
| Calcium (mg/dl) | 8.6 (±0.7) | 8.5 (±0.5) | 8.6 (±0.4) | 8.6 (±0.7) | 8.6 (±0.9) |
| Phosphate (mg/dl) | 5 (±1.4) | 3.9 (±0.8) | 4.7 (±1.0) | 5.4 (±1.3) | 5.8 (±1.7) |
EF, ejection fraction; iFGF, intact fibroblast growth factor; LA, left atrium; LV, left ventricle; TR, tricuspid regurgitation
a
Data are reported as mean (±SD) for continuous variables, and % for categorical variables.
b
Left ventricular wall thickness >11 mm is defined as LV hypertrophy.
c
E (transmitral early filling velocity) / A (transmitral late filling velocity) ratio.