Table 4a.
TREATMENT (mg/kgbw) | Organ weights (g) |
|||||
---|---|---|---|---|---|---|
Liver | Kidneys | Spleen | Heart | Lungs | Brain | |
Normal Control | 10.3 ± 0.4b | 2.0 ± 0.1b | 1.1 ± 0.1a | 1.0 ± 0.1b | 2.9 ± 0.3b | 2.1 ± 0.1b |
Negative Control | 23.1 ± 0.7a | 5.6 ± 0.2a | 0.2 ± 0.1b | 3.8 ± 0.3a | 9.1 ± 0.4a | 4.6 ± 0.4a |
Positive Control | 6.2 ± 0.4c | 1.6 ± 0.1bc | 0.7 ± 0.5a | 0.5 ± 0.1bc | 2.2 ± 0.1c | 1.6 ± 0.1bc |
HFD+200 mg/kg | 6.7 ± 0.2c | 1.3 ± 0.1bc | 0.7 ± 0.5a | 0.5 ± 0.1bd | 1.9 ± 0.1cd | 1.5 ± 0.1bc |
HFD+250 mg/kg | 6.6 ± 0.3c | 1.1 ± 0.1c | 0.7 ± 0.3a | 0.4 ± 0.1de | 1.8 ± 0.1d | 1.5 ± 0.1bc |
HFD+ 300 mg/kg | 6.1 ± 0.1c | 1.1 ± 0.4c | 0.6 ± 0.1a | 0.3 ± 0.1e | 1.5 ± 0.1d | 1.4 ± 0.1c |
Results are expressed as Means ± SD for five animals per group. The means of organ weights within respective columns followed by a superscript of similar lower-case letter (such as [a], [b, ab, bc & bd], [c, bc & cd], [d, bd & cd] or [e & de]) are not significantly different from each other (p > 0.01). However, in each column, means followed by superscripts of different lower-case letter (such as a, b, c, d & e) are significantly different from each other (p ≤ 0.01). Inferential statistics were performed using One way-ANOVA to test for statistical differences among studied groups. Tukey's post hoc test was then done for pairwise separation and comparison of means.