Table 4b.
TREATMENT (mg/kgbw) | Relative Organ to Body Weights (Somatic Index) (%) |
|||||
---|---|---|---|---|---|---|
Liver | Kidney | Spleen | Heart | Lungs | Brain | |
Normal Control | 4.5 ± 0.4b | 0.9 ± 0.1b | 0.5 ± 0.1a | 0.4 ± 0.0b | 1.2 ± 0.1b | 0.9 ± 0.1b |
Negative Control | 7.1 ± 0.1a | 1.7 ± 0.1a | 0.1 ± 0.0b | 1.2 ± 0.1a | 2.8 ± 0.1a | 1.4 ± 0.1a |
Positive Control | 3.2 ± 0.2e | 0.8 ± 0.1b | 0.4 ± 0.2a | 0.3 ± 0.0b | 1.1 ± 0.1bc | 0.9 ± 0.1bc |
HFD+200 mg/kg | 3.9 ± 0.2c | 0.8 ± 0.1b | 0.4 ± 0.3a | 0.3 ± 0.0b | 1.1 ± 0.0bc | 0.8 ± 0.1bc |
HFD+250 mg/kg | 3.7 ± 0.4cd | 0.7 ± 0.1b | 0.3 ± 0.1ab | 0.2 ± 0.0c | 1.0 ± 0.0cd | 0.8 ± 0.0bc |
HFD+ 300 mg/kg | 3.4 ± 0.1de | 0.7 ± 0.1b | 0.2 ± 0.1ab | 0.2 ± 0.0c | 0.9 ± 0.1d | 0.7 ± 0.1c |
Results are expressed as Means ± SD for five animals per group. The means of organo-somatic indices within respective columns followed by a superscript of similar lower-case letter (such as [a & ab], [b & bc], [c, bc & cd], [d & cd] or [e & de]) are not significantly different from each other (p > 0.01). However, in each column, means followed by superscripts of different lower-case letter (such as a, b, c, d & e) are significantly different from each other (p ≤ 0.01). Inferential statistics were performed using One way-ANOVA to test for statistical differences among studied groups. Tukey's post hoc test was then done for pairwise separation and comparison of means.