Table 5.
TREATMENT (mg/kgbw) | Fat Pad Weight (g) |
||||||
---|---|---|---|---|---|---|---|
MESENTERIC | RETROPERITONEAL | PARAMETRIAL | PERIRENAL | SUBCUTANEOUS | BAT | TOTAL FAT | |
Normal Control | 2.8 ± 0.3b | 1.3 ± 0.1b | 0.3 ± 0.1b | 2.2 ± 0.3b | 2.6 ± 0.1d | 0.3 ± 0.1b | 9.4 ± 0.3bc |
Negative Control | 5.9 ± 0.3a | 4.1 ± 0.1a | 0.4 ± 0.1a | 4.1 ± 0.3a | 6.7 ± 0.2a | 1.2 ± 0.1a | 22.5 ± 0.4a |
Orlistat-30 mg/kg | 2.6 ± 0.1bc | 1.3 ± 0.1b | 0.2 ± 0.1c | 2.0 ± 0.2b | 3.9 ± 0.3b | 0.2 ± 0.0c | 10.0 ± 0.4b |
HFD+200 mg/kg | 2.2 ± 0.2cd | 1.4 ± 0.2b | 0.2 ± 0.0c | 1.9 ± 0.1bc | 3.2 ± 0.4c | 0.1 ± 0.1c | 9.000.8c |
HFD+250 mg/kg | 2.0 ± 0.2d | 1.2 ± 0.1b | 0.1 ± 0.01c | 1.5 ± 0.1cd | 2.9 ± 0.2cd | 0.1 ± 0.0c | 7.8 ± 0.3d |
HFD+ 300 mg/kg | 1.9 ± 0.1d | 1.3 ± 0.3b | 0.1 ± 0.0c | 1.4 ± 0.1d | 2.7 ± 0.2d | 0.1 ± 0.1c | 7.4 ± 0.3d |
Results are expressed as Means ± SD for five animals per group. The means of fat pad weights within respective columns followed by a superscript of similar lower-case letter (such as [a], [b & bc], [c, bc & cd] or [d & cd]) are not significantly different from each other (p > 0.01). However, in each column, means followed by superscripts of different lower-case letter (such as a, b, c & d) are significantly different from each other (p ≤ 0.01). Inferential statistics were performed using One way-ANOVA to test for statistical differences among studied groups. Tukey's post hoc test was then done for pairwise separation and comparison of means.