Table 6.
Effect of oral administration of DCM leaf extract of Gnidia glauca on lipid in HFD-Induced obese rats.
| TREATMENT (mg/kgbw) | Lipid Profiles (mmol/L) |
||||
|---|---|---|---|---|---|
| TG | TC | HDL-C | LDL-C | VLDL | |
| Normal Control | 1.44 ± 0.11b | 1.62 ± 0.13d | 1.10 ± 0.16c | 0.50 ± 0.16b | 0.29 ± 0.02b |
| Negative Control | 2.74 ± 0.52a | 4.34 ± 0.13a | 0.64 ± 0.21d | 3.70 ± 0.16a | 0.54 ± 0.10a |
| Positive Control | 1.02 ± 0.16bc | 1.78 ± 0.18cd | 1.34 ± 0.11bc | 0.48 ± 0.13b | 0.20 ± 0.03bc |
| HFD+200 mg/kg | 0.98 ± 0.13bc | 2.12 ± 0.13b | 1.36 ± 0.15bc | 0.52 ± 0.11b | 0.20 ± 0.03bc |
| HFD+250 mg/kg | 0.96 ± 0.11c | 1.90 ± 0.12bc | 1.50 ± 0.10ab | 0.40 ± 0.13b | 0.19 ± 0.02c |
| HFD+ 300 mg/kg | 0.84 ± 0.15c | 1.86 ± 0.15cd | 1.76 ± 0.11a | 0.36 ± 0.15b | 0.17 ± 0.03c |
Results are expressed as Means ± SD for five animals per group. The means of various lipid profiles within respective columns followed by a superscript of similar lower-case letter (such as [a & ab], [b & bc], [c, bc & cd] or [d & cd]) are not significantly different from each other (p > 0.01). However, in each column, means followed by superscripts of different lower-case letter (such as a, b, c & d) are significantly different from each other (p ≤ 0.01). Inferential statistics were performed using One way-ANOVA to test for statistical differences among studied groups. Tukey's post hoc test was then done for pairwise separation and comparison of means.