Figure 5.

Effects of dynamic parameters on the steady-state mean length. Higher catastrophe frequency (A) and rescue frequency (B) shorten the mean length, whereas increasing the shrinkage rate leads to a longer average length (C). The mean length change is small. (D) The mean length depends only weakly on the probability that a newly generated plus end starts in the growing state, denoted by q. Earlier in this analysis we assumed that q = 0. (E) The amplification rate (solid circles) increases strongly with the probability that a newly generated plus end starts in the growing state. This increase is mainly due to the decrease in the rate of disappearance of microtubules (open squares).