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. 2019 Nov 29;6:430. doi: 10.3389/fvets.2019.00430

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Copyright © 2019 Cassmann, Moore, Smith and Greenlee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Western blot comparing multiple ruminant TSEs including L-BSE, scrapie, bovine TME (bTME), and ovine passaged bTME (o-bTME). The blot was immunolabeled with Sha31 anti-PrP antibody after acetone precipitation. The characteristics of bTME in sheep are similar to 3rd passage bTME in cattle that resembles L-BSE. Scrapie has a distinct migration pattern.