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. 2019 Oct 25;9(11):293. doi: 10.3390/brainsci9110293

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The hematoxylin and eosin (H&E) staining and transmission electron microscopy (TEM) images. (A) Contra-lesional and Ipsi-lesional hemispheres of nine weeks stroke brain tissues showing the regions of interest—peri-infract zone (PIZ) and white matter (WM). (B_a) Representative TEM images of contra-lesional cortex (unaffected neurons), whereas (B_b) representing ipsi-lesional PIZ (affected side) and (B_c–d) representing ipsi-lesional WM showing the ultrastructural changes—axonal shearing, formation of vacuoles and swelling marked with black arrows on the images. Scale bar = 100 µm for H&E and 1 µm for TEM.