ADAM	a disintegrin and metalloprotease
AOM	azoxymethane
APC	adenomatous polyposis coli protein
COPD	chronic obstructive pulmonary disease
DSS	dextransulfate sodium
EAE	experimental autoimmune encephalomyelitis
EGF	epidermal growth factor
FDA	US food and drug administration
FoxP3	forkhead box protein 3
FRMD	FERM domain containing protein, identical to iTAP
Gp130	glycoprotein 130 kDa
IECs	intestinal epithelial cells
IFN	interferon
IL-6	Interleukin-6
IL-6R	Interleukin-6 receptor
iRhom	inactive rhomboid protease
iTAP	iRhom Tail-Associated Protein identical to FRMD8
JAK	Janus kinase
JNK	c-Jun N-terminal kinase
Kras	oncogene first identified in Kirsten RAt Sarcoma virus
MAP	mitogen-activated protein
mTOR	mechanistic target of rapamycin
NFκB	nuclear factor kappa-light-chain-enhancer
Notch	cell signaling receptor present in most animals
PTPN	tyrosine phosphatase
RANK	Receptor Activator of NFκB
RANKL	ligand of RANK
ROSA26	reverse oriented splice acceptor, Clone 26
SHP2	protein-tyrosine phosphatase shp2
SOCS	suppressor of cytokine signaling
Src	proto-oncogene tyrosine-protein kinase
STAT	signal transducer and activator of transcription
TNF	tumor necrosis factor
WHO	world health organization
YAP	proto-oncogene yes associated protein.