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. 2019 Oct 24;11(11):1635. doi: 10.3390/cancers11111635

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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SLUG-induced transcriptional changes are associated with recurrence in GBM patients. (A) Heatmap representing the expression of the 180 genes of the SLUG_OE score in 172 TCGA GBM samples. Samples were ranked according to the SLUG_OE score. (B) Scatter plot showing correlation between the SLUG_OE score and the proneural to mesenchymal score and association with recurrent samples (annotated with a star). (C) Box and whiskers plot (min to max) showing increased SLUG_OE score in recurrent compared primary GBMs and normal brain tissue samples.