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ΔΔCq time-averaged differences of miRNAs between subjects HCC+ vs. HCC−. The estimates were obtained using bootstrapped random-effect generalized least square regression (RE-GLS). Internal cross-validation was performed using bootstrap on 1000 samples with replacement (see statistical analysis for details). The difference is calculated as (HCC+ minus HCC−), values showing 95% CI crossing 0 are not statistically significant at the 0.05 level.
