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. 2019 Oct 24;11(11):1637. doi: 10.3390/cancers11111637

Figure 7.

Figure 7

Effects of Gal, NGGAs and ENZ in an in vivo castration-resistant prostate cancer model. (A) Mice bearing CWR22Rv1 xenografts (5 mice per group) were treated with vehicle, Gal (100 mg/kg/twice daily), VNPP414 (60 mg/kg, once daily), VNPP433-3β (15 or 30 mg/kg, once daily) and ENZ (25 mg.kg, once daily) 5 days per week for 16 days. Tumor volumes were measured twice a week and the tumors were collected. Tumor growth inhibition (TGI) values are indicated at the right of each growth curve, and the error bars are the SEM. Results are represented as means ± SEM. # p = ns (not significant vs. vehicle), $ p < 0.0272 vs. vehicle, * p < 0.0035 vs. vehicle, ** p < 0.0025 vs. vehicle and *** p < 0.0008 vs. vehicle. (B) Photographed tumors from each group. (C) Mean body weights of mice determined during the study. (D) Western blot analyses of tumor samples from each experimental group at day 16.