Table 2.

Comparison of the results of DNA methylation/gene expression correlation analysis from the study that used HM450K data and NGS-based transcriptomic profile (investigation group) and the validation study performed by pyrosequencing and qRT-PCR (validation group).

HM450K CpG Site	CpG Location	Gene	Investigation Group Spearman R; p-Value	Validation Group Spearman R; p-Value
cg26334801	5′UTR	FAM163A	−0.802; p < 0.0001	−0.688; p < 0.0001
cg16672562	5′UTR	HIF3A	−0.407; p = 0.0291	−0.380; p = 0.0005
cg05286653	Gene body	HIF3A	−0.490; p = 0.0076	−0.451; p < 0.0001
cg08775835	1stExon	PRSS8	−0.786; p < 0.0001	−0.487; p < 0.0001
cg13439730	1stExon	PRSS8	−0.559; p = 0,0016	−0.484; p < 0.0001
cg27436259	1stExon	PRSS8	−0.744; p < 0.0001	−0.568; p < 0.0001
cg03363863	1stExon	PRSS8	−0.765; p < 0.0001	−0.539; p < 0.0001