Table 3.
Clinical characteristics of pituitary adenoma patients.
| Genome-Wide DNA Methylation/Whole Transcriptome Profiling | DNA Pyrosequencing/qRT-PCR | |
|---|---|---|
| NFPA patients (number of patients) | 32 | 83 |
| Age (years) | ||
| Range | 36–85 | 34–82 |
| Median | 61 | 63 |
| Gender (number of patients) | ||
| Male | 21 | 47 |
| Female | 11 | 36 |
| Histopathology (number of patients) | ||
| Gonadotroph PA | 31 | 76 |
| Null-cell/ Gonadotroph PA* | 1 | 7 |
| Clinical classification (number of patients) | ||
| Invasive NFPA | 17 | 50 |
| Non-invasive NFPA | 15 | 26 |
| Unknown | - | 7 |
* null cell adenomas with clear ultrastructural gonadotroph features.