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. 2019 Nov 8;11(11):1762. doi: 10.3390/cancers11111762

Figure 2.

Figure 2

Genetic knockdown of DOCK1 suppresses cell growth and motility of claudin-low breast cancer cells. Claudin-low breast cancer cells were treated with specific shRNA against DOCK1 (shDOCK1) for three days. Depletion of DOCK1 by shDOCK1 (A) inhibited cell viability (B), clonogenic activity (C), migration (D), and invasion (E). The results are expressed as the mean ± SE from three independent experiments. * p < 0.05; ** p < 0.01, compared with the control group (shLuc).