Table 5.

Association of genetic risk scores (GRS) with fasting glucose level (A) and T2DM status (B) by study groups. The association was evaluated under adjusted regression models (sex, age, BMI, HDL-C, and TG level). OR, odds ratio; CI, confidence interval.

A	Fasting Glucose Level
	Hungarian General Population			Roma Population
	β	95% CI	p-Value	β	95% CI	p-Value
GRS	0.053	0.023–0.082	0.001	0.044	0.003−0.085	0.037
Sex (male as reference)	−0.432	−0.602 to −0.262	<0.001	−0.033	−0.264 to 0.200	0.775
Age	0.042	0.351–0.050	<0.001	0.022	0.013–0.031	<0.001
BMI	0.028	0.011–0.046	0.001	0.048	0.035–0.061	<0.001
HDL-C	−0.313	−0.532 to −0.929	0.005	−0.601	−0.899 to −0.303	<0.001
TG	0.021	−0.038–0.079	0.486	0.151	0.063–0.238	0.001
B	T2DM Status
	Hungarian General Population			Roma Population
	OR	95% CI	p-Value	OR	95% CI	p-Value
GRS	1.07	1.008–1.137	0.027	1.083	1.020–1.151	0.01
Sex (male as reference)	0.385	0.271–0.547	<0.001	0.701	0.505–0.973	0.034
Age	1.069	1.052–1.086	<0.001	1.03	1.016–1.045	<0.001
BMI	1.09	1.052–1.130	<0.001	1.031	1.012–1.051	0.001
HDL-C	0.897	0.571–1.410	0.638	0.628	0.406–0.970	0.036
TG	1.242	1.095–1.411	0.001	1.54	1.347–1.761	<0.001