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Comparison of CTC and ctDNA detection (A–C) CTCs, total ctDNA and ctDNA < 150 bp detected in patients with primary tumors (Breslow depth), lymph node metastasis (LN) and distant metastasis (M) (D,E) Time course of CTC detection, ctDNA, mutations detected in both CTCs and ctDNA, LDH and S100 serum levels in patients 2 and 3. (F) Mutational status for each detection method compared to the primary melanoma.
