Figure 2.

Sequence of human protein RNF135 and their positive selected sites. Representation of the structure of the cytoplasmic protein RNF135 and its 432 amino acids. The orange rectangle represents the cell membrane. The small circles represent the amino acids of the protein, with the names indicated by the letters contained within the circles. The beginning and end of the sequence corresponding to the RING finger domain are indicated by the first and second black arrows respectively. The circles painted in red represent the 27 amino acids that are under positive selection. The green square represents the N-glycosilated motif.