Table 1.
Cumulative adrenocortical tumor (ACT) incidence among TP53 R337H carriers, ACT cases, and relative risk (RR) per subregion based on the 2006-C data.
| ACT and Carriers | Subregion | |||||||
|---|---|---|---|---|---|---|---|---|
| C1 | C2 | C3 | Total | |||||
| ACT cases <10 years of age | 7 | 34 | 36 | 77 | ||||
| Carriers without ACT | 730 | 1819 | 1536 | 4085 | ||||
| Total | 737 | 1853 | 1572 | 4162 | ||||
| ACT | ||||||||
| Subregion | N | C.I. | Subregion | N | C.I. | RR | p Value | |
| (/1000) | (/1000) | X2 | Fischer | |||||
| C2 | 34 | 18.3 | C1 | 7 | 9.5 | 1.932 [0.86; 4.338] | 0.146 | 0.118 |
| C3 | 36 | 22.9 | C2 | 34 | 18.3 | 1.248 [0.785; 1.985] | 0.414 | 0.397 |
| C3 | 36 | 22.9 | C1 | 7 | 9.5 | 2.411 [1.078; 5.392] | 0.04 | 0.031 |
C.I., cumulative incidence. Three ACT cases in adults were not included in this analysis.