Table 2.
Toxicity analysis of 95 patients evaluable for toxicity. The most common toxicities are listed according to frequency of minor toxicity, grade 1–2, and major toxicity, grade 3–4.
| Adverse Event | Grade 1–2 N (%) |
Grade 3–4 N (%) |
|---|---|---|
| Hypertension | 31 (33%) | 8 (8%) |
| Hand-foot-skin reaction | 48 (51%) | 6 (6%) |
| Rash | 20 (21%) | 6 (6%) |
| Fatigue | 77 (81%) | 4 (4%) |
| Diarrhea | 35 (37%) | 3 (3%) |
| Anorexia | 60 (63%) | 2 (2%) |
| Oral mucositis | 43 (45%) | 2 (2%) |
| Nausea | 35 (37%) | 1 (1%) |
| Voice changes | 66 (69%) | 0 (0%) |
| Conjunctivitis | 19 (20%) | 0 (0%) |
| Bleeding | 16 (17%) | 0 (0%) |
| Other toxicites | 65 (68%) | 19 (20%) |