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. 2019 Dec 6;2019(12):CD011207. doi: 10.1002/14651858.CD011207.pub2

Crockett 2006.

Methods Design: cluster‐RT
Groups: intervention (depression management); control (usual care)
Participants Pharmacies: 32
Pharmacy worker: not reported
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Pharmacy user: 106 patients with depression
  • mean age: intervention 46 (SD: 12 years); control 46 (SD: 15 years)

  • % female: intervention 76%; control 82%


Setting: rural
Country: Australia
Interventions Pharmacy worker‐directed intervention: intervention pharmacists were given video‐conference training on the nature and management of depression and were asked to dispense medication with extra advice and support.
  • Delivered by: a psychiatrist, psychologist and GP

  • Type: education; disease management

  • Mode of delivery: video/DVD (video‐conference training)

  • TDF: knowledge, skills, environment, context and resources

  • Duration: not reported


Pharmacy worker control: usual care
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Pharmacy user‐directed intervention: education on depression management; patient’s psychological well‐being monitoring, attitudes towards taking antidepressants, adherence and patient satisfaction with service.
  • Delivered by: pharmacists.

  • Type: education; disease management.

  • Mode of delivery: individual face‐to‐face; video/DVD; written materials

  • TDF: knowledge, emotion

  • Duration: variable; an initial visit and then, to quote, "checking ‘how they were going’ at subsequent visits to the pharmacy".


Follow‐up: 3 months
Pharmacy user control: usual care
Outcomes Pharmacy worker: not assessed
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Pharmacy user:
  • Clinical: not assessed.

  • Psychological health: patients' well‐being (K10)

  • Behavioural: adherence

  • Quality of life: not assessed

  • Process: patient satisfaction with service; attitude towards taking antidepressants (using the Drug Attitude Index (DAI)).

  • Costs: not assessed.

Notes Study/intervention name: none given
Funding source: grant from the Rural and Remote Pharmacy Infrastructe Grants scheme
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Randomised, but no specific method mentioned.
Allocation concealment (selection bias) Unclear risk Not mentioned
Baseline outcome measures similar Unclear risk Baseline differences unclear
Baseline characteristics similar Low risk No differences in the characteristics reported, but reported adjustment in analyses for baseline differences
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Nothing noted
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not mentioned
Protection against contamination High risk Randomisation at pharmacist level but four of control pharmacies were delivering similar intervention
Selective reporting (reporting bias) Low risk Nothing noted.
Other bias Unclear risk Assessments may have impacted outcome
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not mentioned