Table 2.
Information on single nucleotide polymorphisms (SNPs) identified in the IL-6 gene.
| NO | SNP Name | Position | Genotype | Genotype Frequency | Allelic Gene | Allele Frequency | χ2 Value | p Value | H | Ne | PIC |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | T-1534C | 30947851 | CC | 0.400 | C | 0.618 | 0.123 | 0.726 | 0.472 | 1.894 | 0.361 |
| TT | 0.164 | T | 0.382 | ||||||||
| CT | 0.436 | ||||||||||
| 2 | C-1280T | 30948105 | CC | 0.636 | C | 0.818 | 1.604 | 0.205 | 0.298 | 1.424 | 0.253 |
| TT | 0 | T | 0.182 | ||||||||
| CT | 0.364 | ||||||||||
| 3 | G-1223A | 30948162 | GG | 0.582 | G | 0.791 | 2.636 | 0.104 | 0.331 | 1.494 | 0.276 |
| AA | 0 | A | 0.209 | ||||||||
| AG | 0.418 | ||||||||||
| 4 | G-1220T | 30948165 | GG | 0.600 | G | 0.800 | 2.260 | 0.133 | 0.320 | 1.471 | 0.269 |
| TT | 0 | T | 0.200 | ||||||||
| GT | 0.400 | ||||||||||
| 5 | A-1208G | 30948177 | AA | 0.600 | G | 0.800 | 2.260 | 0.133 | 0.320 | 1.471 | 0.269 |
| GG | 0 | T | 0.200 | ||||||||
| AG | 0.400 | ||||||||||
| 6 | C-939G | 30948446 | CC | 0.418 | C | 0.618 | 0.840 | 0.359 | 0.472 | 1.894 | 0.361 |
| GG | 0.182 | G | 0.382 | ||||||||
| CG | 0.400 | ||||||||||
| 7 | G-889A | 30948496 | GG | 0.254 | G | 0.545 | 1.173 | 0.279 | 0.496 | 1.984 | 0.361 |
| AA | 0.164 | A | 0.455 | ||||||||
| AG | 0.582 | ||||||||||
| 8 | G-865A | 30948520 | AA | 1 | A | 1 | 0.000 | 1.000 | 0.000 | ||
| GG | 0 | G | 0 | ||||||||
| AG | 0 | ||||||||||
| 9 | G-791C | 30948594 | GG | 0.218 | G | 0.518 | 1.675 | 0.196 | 0.499 | 1.998 | 0.375 |
| CC | 0.182 | C | 0.482 | ||||||||
| GC | 0.600 | ||||||||||
| 10 | G-734A | 30948651 | GG | 0.473 | G | 0.682 | 0.007 | 0.933 | 0.434 | 1.766 | 0.400 |
| AA | 0.109 | A | 0.318 | ||||||||
| GA | 0.418 | ||||||||||
| 11 | A-663G | 30948722 | GG | 1 | G | 1 | 0.000 | 1.000 | 0.000 | ||
| AA | 0 | A | 0 | ||||||||
| GA | 0 | ||||||||||
| 12 | A-634G | 30948751 | GG | 0.473 | G | 0.700 | 0.133 | 0.715 | 0.420 | 1.724 | 0.332 |
| AA | 0.073 | A | 0.300 | ||||||||
| GA | 0.454 | ||||||||||
| 13 | G-610A | 30948775 | GG | 0.527 | G | 0.764 | 3.966 | 0.046 | 0.361 | 1.565 | 0.296 |
| AA | 0.000 | A | 0.236 | ||||||||
| GA | 0.473 | ||||||||||
| 14 | C-511T | 30948874 | TT | 0.545 | T | 0.745 | 0.020 | 0.888 | 0.380 | 1.612 | 0.307 |
| CC | 0.055 | C | 0.255 | ||||||||
| TC | 0.400 | ||||||||||
| 15 | A-483G | 30948902 | AA | 0.454 | A | 0.691 | 0.302 | 0.583 | 0.427 | 1.746 | 0.336 |
| GG | 0.073 | G | 0.309 | ||||||||
| AG | 0.473 | ||||||||||
| 16 | T-458G | 30948927 | TT | 0.327 | T | 0.582 | 0.022 | 0.882 | 0.487 | 1.948 | 0.368 |
| GG | 0.164 | G | 0.418 | ||||||||
| TG | 0.509 | ||||||||||
| 17 | C-447G | 30948938 | CC | 0.455 | C | 0.682 | 0.018 | 0.893 | 0.434 | 1.766 | 0.400 |
| GG | 0.091 | G | 0.318 | ||||||||
| CG | 0.454 | ||||||||||
| 18 | A-400G | 30948985 | GG | 0.964 | G | 0.982 | 12.882 | 0.000 | 0.036 | 1.037 | 0.035 |
| AA | 0 | A | 0.018 | ||||||||
| AG | 0.036 | ||||||||||
| 19 | G-357A | 30949028 | GG | 0.291 | G | 0.518 | 0.219 | 0.640 | 0.499 | 1.997 | 0.375 |
| AA | 0.254 | A | 0.482 | ||||||||
| AG | 0.455 |
Note: PIC: Polymorphism information content (PIC > 0.5 indicates highly polymorphic; 0.25 < PIC < 0.5 indicates moderately polymorphic; PIC < 0.25 indicates lowly polymorphic); H: Heterozygosity; Ne: Effective number of alleles.