Table 3.
Associations of nine SNPs in the IL-6 gene with the E. tenella resistance indexes in chickens.
| Mutation Site | Genotype | NO (μmol/L) | CAT (U/L) | SOD (U/L) | IL-17 (pg/mL) | GSH-Px (U/L) | MDA (mmol/L) | IL-2 (ng/L) | IL-16 (ng/L) | IFN-γ (ng/L) | β-Carotene (μmol/L) | Weight Gain (g) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T-1534C | CC | 55.92 ± 5.17 | 66.25 ± 10.54 | 126.23 ± 14.42 | 37.36 ± 5.41 | 482.33 ± 83.44 | 5.70 ± 0.76 Bb | 29.71 ± 3.34 | 52.15 ± 7.60 | 37.19 ± 6.02 | 63.40 ± 26.13 | 33.09 ± 26.14 |
| TT | 52.33 ± 5.73 | 63.54 ± 14.61 | 117.56 ± 29.92 | 35.56 ± 9.78 | 449.50 ± 60.79 | 5.10 ± 0.94 ABb | 33.27 ± 5.70 | 55.34 ± 11.23 | 34.65 ± 2.55 | 67.42 ± 16.90 | 43.73 ± 15.79 | |
| CT | 54.18 ± 5.40 | 61.83 ± 10.03 | 120.44 ± 19.71 | 40.23 ± 8.65 | 443.38 ± 66.52 | 5.98 ± 0.79 Aa | 34.57 ± 6.06 | 53.04 ± 7.15 | 35.62 ± 4.08 | 66.40 ± 29.01 | 69.55 ± 114.34 | |
| C-939G | CC | 56.99 ± 5.22 | 65.82 ± 11.00 | 126.14 ± 14.55 | 37.14 ± 4.97 | 509.62 ± 88.23 | 5.72 ± 0.77 Bb | 30.17 ± 3.85 | 51.28 ± 8.62 | 37.16 ± 6.05 | 60.55 ± 23.18 | 36.75 ± 22.49 |
| GG | 52.20 ± 4.88 | 61.96 ± 12.70 | 116.14 ± 25.65 | 36.69 ± 9.46 | 434.06 ± 60.67 | 5.20 ± 0.85 ABb | 31.61 ± 6.18 | 54.40 ± 9.85 | 34.48 ± 2.22 | 73.80 ± 19.00 | 36.84 ± 22.32 | |
| CG | 53.83 ± 5.32 | 62.53 ± 10.27 | 121.35 ± 20.36 | 40.37 ± 8.83 | 433.93 ± 47.83 | 6.02 ± 0.79 Aa | 35.12 ± 5.67 | 53.66 ± 6.65 | 35.81 ± 4.23 | 65.31 ± 30.16 | 72.88 ± 119.70 | |
| G-889A | GG | 53.39 ± 5.08 | 59.09 ± 12.07 | 126.83 ± 28.18 | 36.55 ± 6.79 | 431.79 ± 45.54 | 5.68 ± 1.24 | 31.31 ± 4.75 ABa | 55.81 ± 7.35 | 35.09 ± 2.22 | 58.64 ± 17.03 | 48.09 ± 18.03 |
| AA | 54.56 ± 3.31 | 63.23 ± 9.43 | 118.92 ± 8.42 | 37.68 ± 6.55 | 482.46 ± 78.25 | 5.99 ± 0.68 | 27.76 ± 3.19 Bb | 53.54 ± 4.23 | 35.01 ± 3.55 | 76.44 ± 31.73 | 34.00 ± 26.98 | |
| GA | 54.77 ± 5.93 | 65.14 ± 10.45 | 120.03 ± 17.82 | 39.81 ± 8.86 | 459.45 ± 77.90 | 5.75 ± 0.68 | 34.79 ± 5.64 Aa | 51.94 ± 8.49 | 36.45 ± 5.36 | 66.42 ± 28.19 | 62.73 ± 111.00 | |
| A-634G | GG | 54.93 ± 5.56 | 62.66 ± 10.95 | 114.96 ± 16.61 | 40.55 ± 6.25 | 462.62 ± 82.99 a | 5.38 ± 0.99 | 31.87 ± 4.90 B | 49.35 ± 9.44 | 36.38 ± 4.84 | 67.48 ± 22.40 | 40.36 ± 22.27 |
| AA | 55.31 ± 4.81 | 68.05 ± 9.15 | 131.36 ± 32.52 | 33.34 ± 7.28 | 386.79 ± 85.77 b | 5.33 ± 1.01 | 30.76 ± 4.71 AB | 54.13 ± 10.38 | 35.92 ± 4.24 | 54.08 ± 16.31 | 55.53 ± 7.66 | |
| AG | 54.38 ± 5.64 | 57.48 ± 11.77 | 117.56 ± 20.52 | 38.97 ± 7.91 | 420.91 ± 45.95b | 5.70 ± 0.81 | 35.95 ± 5.73 A | 53.56 ± 8.41 | 37.32 ± 5.04 | 62.50 ± 30.51 | 68.07 ± 106.66 | |
| C-511T | TT | 55.68 ± 5.19 a | 61.54 ± 11.50 | 120.39 ± 19.95 | 38.34 ± 7.63 | 424.69 ± 63.35 | 5.53 ± 0.80 | 33.64 ± 6.15 | 51.97 ± 8.36 | 36.64 ± 5.09 | 64.95 ± 32.25 | 65.25 ± 97.93 |
| CC | 49.13 ± 5.34 b | 56.24 ± 7.86 | 100.24 ± 8.98 | 45.90 ± 3.36 | 425.87 ± 52.67 | 4.77 ± 0.90 | 35.57 ± 1.55 | 48.27 ± 13.37 | 37.97 ± 2.03 | 80.04 ± 18.71 | 67.43 ± 11.22 | |
| CT | 54.14 ± 5.54 ab | 60.14 ± 12.15 | 115.49 ± 19.73 | 39.72 ± 6.73 | 458.16 ± 7.23 | 5.60 ± 1.04 | 33.39 ± 5.29 | 51.57 ± 9.95 | 36.78 ± 4.87 | 61.12 ± 14.81 | 36.97 ± 17.39 | |
| A-483G | GG | 55.31 ± 4.81 | 68.05 ± 9.15 | 131.36 ± 32.52 | 39.98 ± 5.65 a | 462.00 ± 84.63 a | 5.33 ± 1.01 | 36.24 ± 5.80 A | 54.13 ± 10.38 | 35.92 ± 4.24 | 54.08 ± 16.31 | 55.53 ± 7.66 |
| AA | 54.85 ± 5.66 | 62.06 ± 10.73 | 113.67 ± 15.58 | 31.34 ± 7.28 b | 386.79 ± 85.77 b | 5.33 ± 0.98 | 31.41 ± 4.40 B | 49.59 ± 9.55 | 36.25 ± 4.90 | 67.41 ± 22.85 | 40.59 ± 22.70 | |
| GA | 54.49 ± 5.56 | 58.26 ± 12.19 | 118.70 ± 20.93 | 39.57 ± 8.34 a | 423.11 ± 46.41 b | 5.74 ± 0.81 | 30.76 ± 4.71 AB | 53.16 ± 8.48 | 37.40 ± 4.95 | 62.76 ± 29.93 | 46.93 ± 16.87 | |
| T-458G | TT | 52.86 ± 5.41 | 59.55 ± 11.43 | 120.15 ± 25.74 | 40.42 ± 7.84 | 428.76 ± 54.92 | 5.51 ± 1.05 | 33.67 ± 5.56 ABb | 53.89 ± 8.51 | 36.49 ± 3.05 | 63.42 ± 17.26 | 50.26 ± 17.31 |
| GG | 55.33 ± 5.47 | 62.75 ± 11.46 | 115.91 ± 8.96 | 39.59 ± 5.34 | 460.75 ± 66.46 | 5.28 ± 1.08 | 28.94 ± 4.49 Bb | 50.62 ± 6.55 | 34.48 ± 3.32 | 73.66 ± 31.80 | 39.59 ± 21.75 | |
| GT | 55.70 ± 5.38 | 60.78 ± 11.88 | 115.98 ± 18.26 | 38.50 ± 7.47 | 436.91 ± 82.92 | 5.60 ± 0.77 | 35.14 ± 5.28 Aa | 50.47 ± 10.16 | 37.69 ± 5.92 | 61.74 ± 28.74 | 42.73 ± 20.08 | |
| C-447G | CC | 55.00 ± 5.66 | 62.99 ± 11.05 | 131.24 ± 28.28 a | 40.76 ± 6.29 a | 461.06 ± 84.30 a | 5.36 ± 1.01 | 35.06 ± 4.90 a | 49.31 ± 9.63 | 36.20 ± 4.86 | 65.59 ± 20.63 | 40.52 ± 22.71 |
| GG | 54.86 ± 4.29 | 65.32 ± 10.01 | 110.53 ± 16.81 b | 33.73 ± 6.37 b | 409.79 ± 90.35 ab | 5.40 ± 0.89 | 30.03 ± 4.40 b | 53.38 ± 9.15 | 36.89 ± 4.27 | 66.21 ± 30.57 | 51.66 ± 10.90 | |
| GC | 54.38 ± 5.64 | 57.49 ± 11.76 | 117.56 ± 20.52 ab | 38.97 ± 7.91 ab | 420.91 ± 45.95 b | 5.70 ± 0.81 | 32.95 ± 5.73 b | 53.56 ± 8.41 | 37.32 ± 5.04 | 62.50 ± 30.51 | 47.43 ± 17.02 | |
| G-357A | GG | 55.17 ± 5.84 | 62.64 ± 11.23 ab | 115.36 ± 20.47 | 43.01 ± 8.87 A | 457.92 ± 97.76 | 5.42 ± 1.00 | 35.07 ± 4.54 | 47.75 ± 10.78 b | 37.77 ± 5.25 | 63.50 ± 16.30 | 41.09 ± 24.06 |
| AA | 54.58 ± 5.25 | 65.27 ± 11.70 a | 123.06 ± 21.04 | 35.71 ± 5.85 B | 425.97 ± 68.38 | 5.63 ± 0.73 | 33.96 ± 5.18 | 55.39 ± 9.02 a | 35.61 ± 4.93 | 64.75 ± 35.90 | 50.62 ± 15.09 | |
| GA | 54.48 ± 5.54 | 56.90 ± 10.72 b | 115.40 ± 18.77 | 38.95 ± 5.76 AB | 432.31 ± 52.09 | 5.52 ± 0.97 | 32.56 ± 6.40 | 51.96 ± 7.24 ab | 36.78 ± 4.56 | 64.43 ± 25.57 | 43.64 ± 18.60 |
Note: a, b within the same column with different superscripts indicate a p-value < 0.05; A, B within the same column with different superscripts indicate a p-value < 0.01.