Table 6.
The top 50 most differentially regulated genes in cancer cell lines following modulation of grh/Grhl function.
| Rank | Gene | Regulation | Normalised Score |
|---|---|---|---|
| 1 | ALOX15 | POSITIVE | 0.045 |
| 2 | CCDC88A | NEGATIVE | 0.0405 |
| 3 | FAT4 | NEGATIVE | 0.0345 |
| 4 | EPCAM | POSITIVE | 0.0345 |
| 5 | IL36RN | POSITIVE | 0.0345 |
| 6 | AHSG | NEGATIVE | 0.0345 |
| 7 | Krt7 | POSITIVE | 0.0345 |
| 8 | Sele | NEGATIVE | 0.0345 |
| 9 | AIM1 | POSITIVE | 0.0285 |
| 10 | CD24 | POSITIVE | 0.0277 |
| 11 | ALOXE3 | POSITIVE | 0.0274 |
| 12 | SOD1 | NEGATIVE | 0.0274 |
| 13 | ITGB6 | POSITIVE | 0.0274 |
| 14 | SERPINE1 | NEGATIVE | 0.0274 |
| 15 | NOX5 | POSITIVE | 0.0274 |
| 16 | ALB | NEGATIVE | 0.0274 |
| 17 | Epcam | POSITIVE | 0.0274 |
| 18 | Ptges | NEGATIVE | 0.0274 |
| 19 | KRT19 | POSITIVE | 0.0263 |
| 20 | TYMS | NEGATIVE | 0.0248 |
| 21 | ALOX12P2 | POSITIVE | 0.0239 |
| 22 | Cat | NEGATIVE | 0.0239 |
| 23 | FGF2 | NEGATIVE | 0.0239 |
| 24 | CRISP3 | POSITIVE | 0.0239 |
| 25 | SYN3 | NEGATIVE | 0.0239 |
| 26 | Cldn4 | POSITIVE | 0.0239 |
| 27 | Otop1 | NEGATIVE | 0.0239 |
| 28 | SLC1A6 | POSITIVE | 0.0217 |
| 29 | NQO1 | NEGATIVE | 0.0217 |
| 30 | TMPRSS13 | POSITIVE | 0.0217 |
| 31 | ATOH8 | NEGATIVE | 0.0217 |
| 32 | Cldn7 | POSITIVE | 0.0217 |
| 33 | Xdh | NEGATIVE | 0.0217 |
| 34 | NCF2 (p67-PHOX) | POSITIVE | 0.0202 |
| 35 | GLUD1 | NEGATIVE | 0.0202 |
| 36 | ITGA2 | POSITIVE | 0.0202 |
| 37 | SMARCA1 | NEGATIVE | 0.0202 |
| 38 | ALDH3B2 | POSITIVE | 0.0202 |
| 39 | BRSK1 | NEGATIVE | 0.0202 |
| 40 | Lamc2 | POSITIVE | 0.0202 |
| 41 | Olfr1372-ps1 | NEGATIVE | 0.0202 |
| 42 | SOD2 | POSITIVE | 0.019 |
| 43 | ITGB8 | POSITIVE | 0.019 |
| 44 | CDH2 | NEGATIVE | 0.019 |
| 45 | A2ML1 | POSITIVE | 0.019 |
| 46 | TMEM45A | NEGATIVE | 0.019 |
| 47 | Tmem54 | POSITIVE | 0.019 |
| 48 | Dnahc6 | NEGATIVE | 0.019 |
| 49 | CDH1 | POSITIVE | 0.0189 |
| 50 | GALNT3 | POSITIVE | 0.0188 |