Table 2.
Volunteer |
Vaccine-associated TCR clones reported by Pogorelyy et al. (2) |
Unique canonical vaccine-associated TCRs identified by Pogorelyy et al. (2) |
Epitope-specific TCRs identified by TCRex |
Overlapping TCRs |
---|---|---|---|---|
P1 | 1,151 | 1090 | 92 | 2 |
P2 | 800 | 763 | 110 | 3 |
Q1 | 576 | 547 | 79 | 7 |
Q2 | 1,685 | 1589 | 92 | 8 |
S1 | 773 | 747 | 170 | 19 |
S2 | 983 | 948 | 273 | 11 |
For each volunteer from Pogorelyy et al. (2) are given: the number of YFV-specific clones (DNA level) reported by the YFV vaccine study, the number of unique canonical YFV-specific TCRs (i.e., TCRs starting with cysteine and ending with phenylalanine) (protein level with CDR3 beta sequences not containing any non-amino acid characters) identified in the YFV vaccine study, the number of epitope-specific sequences in the post-vaccination repertoire identified by TCRex and the number of TCRs identified by both the YFV vaccine study and TCRex.