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. 2019 Nov 29;10:2820. doi: 10.3389/fimmu.2019.02820

Table 2.

Comparison of the epitope-specific TCR sequences identified with TCRex to the results from Pogorelyy et al. (2).

Volunteer Vaccine-associated
TCR clones reported by Pogorelyy et al. (2)
Unique canonical vaccine-associated
TCRs identified by
Pogorelyy et al. (2)
Epitope-specific
TCRs identified by TCRex
Overlapping
TCRs
P1 1,151 1090 92 2
P2 800 763 110 3
Q1 576 547 79 7
Q2 1,685 1589 92 8
S1 773 747 170 19
S2 983 948 273 11

For each volunteer from Pogorelyy et al. (2) are given: the number of YFV-specific clones (DNA level) reported by the YFV vaccine study, the number of unique canonical YFV-specific TCRs (i.e., TCRs starting with cysteine and ending with phenylalanine) (protein level with CDR3 beta sequences not containing any non-amino acid characters) identified in the YFV vaccine study, the number of epitope-specific sequences in the post-vaccination repertoire identified by TCRex and the number of TCRs identified by both the YFV vaccine study and TCRex.