Table 3.
LLWNGPMAV-specific enrichment analysis results for all volunteers from Pogorelyy et al. (2).
| Volunteer |
Identification level pre-vaccination PBMC |
Identification level post-vaccination PBMC |
|||||
|---|---|---|---|---|---|---|---|
|
Identified TCRs |
% epitope-specific TCRs | Adjusted p-value enrichment analysis vs. background repertoire |
Identified TCRs |
% epitope-specific TCRs | Adjusted p-value enrichment analysis vs. background repertoire | Adjusted p-value enrichment analysis vs. pre-vaccination repertoire | |
| P1 | 77 | 0.007272 | 0.999 | 92 | 0.010400 | 0.441 | 8.17e-04 |
| P2 | 95 | 0.008119 | 0.999 | 110 | 0.009614 | 0.673 | 0.045 |
| Q1 | 61 | 0.008615 | 0.999 | 79 | 0.017915 | 2.80e-06 | 1.24e-08 |
| Q2 | 109 | 0.008440 | 0.999 | 92 | 0.015455 | 8.59e-05 | 1.64e-07 |
| S1 | 138 | 0.014311 | 2.40e-04 | 170 | 0.025194 | 6.06e-25 | 5.69e-11 |
| S2 | 180 | 0.013314 | 4.09e-04 | 273 | 0.017962 | 2.10e-18 | 2.03e-06 |
The table represents the adjusted p-values (Benjamini-Hochberg adjusted p-values for 6 tests) associated with the LLWNGPMAV-specific enrichment analyses for both full (i.e., derived from PBMC) pre- and post-vaccination TCR repertoires. In addition, the number of identified specific TCRs and the percentage of identified specific TCRs are given.