Table 4.

LLWNGPMAV-specific enrichment analysis results for all volunteers from Dewitt et al. (1).

Volunteer	Pre-vaccination full TCR repertoire			Post-vaccination full TCR repertoire				Post-vaccination activated TCR repertoire
	Identified TCRs	% epitope- specific TCRs	Adjusted p-value enrichment analysis vs. background repertoire	Identified TCRs	% epitope- specific TCRs	Adjusted p-value enrichment analysis vs. background repertoire	Adjusted p-value enrichment analysis vs. pre-vaccination repertoire	Identified TCRs	% epitope- specific TCRs	Adjusted p-value enrichment analysis vs. background repertoire	Adjusted p-value enrichment analysis vs. pre-vaccination repertoire
1	35	0.010813	0.621	32	0.009094	0.935	0.857	4	0.017189	0.265	0.316
2	48	0.012999	0.384	65	0.015565	1.56e-03	0.212	5	0.028991	0.056	0.116
3	41	0.012539	0.384	87	0.025967	9.29e-14	7.86e-09	181	0.550922	1.86e-239	5.00e-222
4	23	0.009778	0.856	34	0.012084	0.299	0.231	21	0.103128	2.56e-14	1.67e-14
5	8	0.012759	0.621	63	0.020710	7.22e-07	9.93e-04	71	0.423527	7.50e-87	1.56e-79
6	41	0.012111	0.384	32	0.012065	0.299	0.684	8	0.040422	2.31e-03	7.45e-03
7	11	0.006771	0.964	11	0.005344	0.992	0.857	2	0.011544	0.517	0.369
8	22	0.008229	0.964	27	0.010866	0.539	0.212	2	0.011869	0.517	0.404
9	13	0.006451	0.964	18	0.008163	0.938	0.284	4	0.021606	0.176	0.060

The table represents the adjusted p-values (Benjamini-Hochberg adjusted p-values for 9 tests) associated with the LLWNGPMAV-specific enrichment analyses for both full (i.e., derived from PBMC) pre- and post-vaccination TCR repertoires and the post-vaccination activated TCR repertoire. In addition, the number of identified specific TCRs and the percentage of identified specific TCRs are given.