Table 5.
Epitope-specific TCRs identified in the enriched CMV-related TCR dataset of Emerson et al. (15) (0.01% BPR threshold).
| TRBV gene | CDR3 beta sequence | TRBJ gene | Epitope | Virus | Class probability score | BPR score |
|---|---|---|---|---|---|---|
| TRBV07-06 | CASSLAPGATNEKLFF | TRBJ01-04 | NLVPMVATV | CMV | 0.99 | 0.0 |
| TRBV30 | CAWSVSDLAKNIQYF | TRBJ02-04 | NLVPMVATV | CMV | 0.91 | 0.0 |
| TRBV09 | CASSALGGAGTGELFF | TRBJ02-02 | NLVPMVATV | CMV | 0.84 | 0.0 |
| TRBV07-03 | CASSRLAGGTDTQYF | TRBJ02-03 | QIKVRVKMV | CMV | 0.54 | 2e-05 |
| TRBV07-09 | CASSLIGVSSYNEQFF | TRBJ02-01 | TPRVTGGGAM | CMV | 0.97 | 0.0 |
| TRBV04-03 | CASSPSRNTEAFF | TRBJ01-01 | TPRVTGGGAM | CMV | 0.92 | 0.0 |
| TRBV04-03 | CASSPQRNTEAFF | TRBJ01-01 | TPRVTGGGAM | CMV | 0.85 | 0.0 |
| TRBV04-03 | CASSPHRNTEAFF | TRBJ01-01 | TPRVTGGGAM | CMV | 0.85 | 0.0 |
| TRBV09 | CASSGQGAYEQYF | TRBJ02-07 | LLWNGPMAV | YFV | 0.98 | 0.0 |