Figure 1.

Timeline of chronic obstructive pulmonary disease (COPD) drug approvals. The timeline depicts the COPD drugs by class and year of first approval in either the US and/or the European Union market. Publication year of regulatory guidance is also shown. ABECB, acute bacterial exacerbations of chronic bronchitis; E‐RS‐COPD, evaluating respiratory symptoms in COPD; EXACT, Exacerbations of Chronic Pulmonary Disease Tool; ICS, inhaled corticosteroids; LABA, long‐acting β2‐adrenoreceptor; LAMA, long‐acting muscarinic antagonists; PDE4, phosphodiesterase type 4; SABA, short‐acting β2‐adrenoreceptor agonist; SAMA, short‐acting muscarinic antagonist; SGRQ, St. George's Respiratory Questionnaire.