Table I.
Association of miR-218 expression with clinicopathological factors in patients with squamous cell carcinoma.
| Factor | N | Relative expression of miR-218 (mean) | P-value |
|---|---|---|---|
| Age (years; mean age, 51.763±1.079) | 0.088 | ||
| <50 | 32 | 5.949±1.625 | |
| ≥50 | 48 | 7.005±0.971 | |
| LNM | 0.004 | ||
| Positive | 37 | 3.586±0.686 | |
| Negative | 43 | 9.051±1.749 | |
| Tumor diameter (cm) | <0.001 | ||
| <4 | 39 | 7.754±0.648 | |
| ≥4 | 41 | 4.324±1.057 | |
| Vessel invasion | 0.002 | ||
| Positive | 29 | 3.526±1.092 | |
| Negative | 51 | 9.231±0.949 | |
| FIGO stage | 0.260 | ||
| IB1-IB2 | 40 | 7.005±0.971 | |
| IIA | 40 | 6.539±1.215 | |
| Differentiation | 0.990 | ||
| Moderate or well | 70 | 7.426±1.057 | |
| Poor | 10 | 7.054±0.634 | |
| HPV status | 0.003 | ||
| Positive | 60 | 4.586±1.042 | |
| Negative | 20 | 8.231±0.934 |
FIGO, International Federation of Gynecology and Obstetrics; HPV, human papillomavirus; LNM, lymph node metastasis; miR-218, microRNA-218.