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Efficacy of the polyethyleneimine-functionalized magnetic iron oxide/CTGF-siRNA complexes (w/w=8) on suppressing CTGF expression in activated LX-2 cells. (A) Reduced CTGF mRNA levels, as quantified by reverse transcription-quantitative PCR analysis (n=3). (B) Reduced protein expression of CTGF, as evaluated by western blot analysis (n=3). *P<0.05 vs. the blank and NC siRNA groups. NC, negative control; siRNA, small interfering RNA; CTGF, connective tissue growth factor.
