Table 1.
Clinical features of overall hypothyroid pregnancies at Aga Khan University
| Clinical characteristics | Frequency (%) N = 708 |
|---|---|
| Age (years) | |
| Age 18–25 | 87 (12.3) |
| Age 26–33 | 403 (56.9) |
| Age 34–40 | 200 (28.2) |
| Age 41–47 | 18 (2.5) |
| Parity | |
| Nulliparous | 216 (31.4) |
| Primiparous | 221 (32.2) |
| Biparous | 140 (20.4) |
| Multiparous | 110 (16.0) |
| Missing | 21 (3.0) |
| Body Mass Index (Kg/m2) | |
| Underweight (< 18.5) | 19 (2.7) |
| Normal (18.5–24.9) | 177 (25.0) |
| Overweight (25–29.9) | 221 (31.2) |
| Obesity class I (30–34.9) | 150 (21.2) |
| Obesity class II and above (> = 35) | 47 (6.6) |
| Unknown | 94 (13.3) |
| Gestational age at antenatal visit (weeks of pregnancy) | 11 (7–19) |
| Mode of labor (for live births only; N = 638) | |
| Spontaneous | 145 (22.7) |
| Induced | 157 (24.6) |
| Augmented | 76 (11.9) |
| Not applicable (because of caesarian section) | 260 (40.8) |
| Mode of delivery (for live births only; N = 638) | |
| Em-LSCS | 149 (23.4) |
| LSCS | 223 (35.0) |
| Instrumental | 23 (3.6) |
| SVD | 87 (13.6) |
| SVD with Episiotomy | 156 (24.5) |
| Gestational age at delivery (weeks) | 38 (37–39) |
| Hypothyroidism diagnosed during pregnancy | |
| Uncategorized | 14 (2.0) |
| Overt hypothyroidism | 13 (1.8) |
| Subclinical hypothyroidism | 43 (6.1) |
| Hypothyroidism diagnosed prior to pregnancy | |
| Uncategorized | 308 (43.5) |
| Overt hypothyroidism | 86 (12.6) |
| Subclinical hypothyroidism | 217 (30.6) |
| Neither preconceptional nor Gestational Hypothyroidism | 27 (3.8) |
| Etiology of Hypothyroidism | |
| Hashimoto’s | 183 (25.8) |
| Post Radioactive Iodine ablation | 8 (1.1) |
| Post-surgical | 6 (0.8) |
| Postpartum thyroiditis | 4 (0.6) |
| Secondary Hypothyroidism | 1 (0.1) |
| After medical treatment for Grave’s Disease | 2 (0.3) |
| Congenital | 1 (0.1) |
| Nodular Goiter | 2 (0.3) |
| Subacute thyroiditis | 1 (0.1) |
| Unknown | 500 (70.6) |
| Thyroid antibodies | |
| Positive | 158 (22.3) |
| Negative | 57 (8.1) |
| Not checked | 493 (69.6) |
| Comorbidities (positive cases only) | |
| Diabetes mellitus | 55 (7.8) |
| Gestational diabetes | 150 (21.2) |
| Hypertension | |
| Pregnancy Induced Hypertension | 75 (10.6) |
| Chronic Hypertension | 34 (4.8) |
| Smoking | 1 (0.1) |
Data are expressed as mean (± standard deviation) or median (interquartile range)