Table 4.
Univariate analysis of maternal outcomes between TSH groups in 1st, 2nd and 3rd trimesters
| 1st Trimester TSH data | 2nd Trimester TSH data | 3rd Trimester TSH data | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Controlled (up to 2.5 mIU/L) N = 170 | Uncontrolled (greater than 2.5 mIU/L) N = 207 | P -value | Controlled (up to 2.5 mIU/L) N = 230 | Uncontrolled (greater than 2.5 mIU/L) N = 207 | P -value | Controlled (up to 2.5 mIU/L) N = 256 | Uncontrolled (greater than 2.5 mIU/L) N = 215 | P -value | |
| Pregnancy Loss | 12 (6.9%) | 26 (11.4%) | 0.12 | 7 (3.0) | 7 (3.4) | 0.8 | 0 (0) | 0 (0) | – |
| Uneventful pregnancy (Live births & twins/triplets & TOP) | 162 (93.1%) | 202 (88.6%) | 223 (97.0) | 200 (96.6) | 256 (100.0) | 215 (100.0) | |||
| Gestational Hypertension | N/A | N/A | 0.13 | ||||||
| Yes | 22 (9.6) | 30 (14.5) | 25 (9.8) | 31 (14.4) | 0.12 | ||||
| No | 208 (90.4) | 177 (85.5) | 231 (90.2) | 184 (85.6) | |||||
| Pre-Eclampsia | N/A | N/A | 0.35 | 0.08 | |||||
| Yes | 12 (5.2) | 7 (3.4) | 7 (2.7) | 13 (6.0) | |||||
| No | 218 (94.8) | 200 (96.6) | 249 (97.3) | 202 (94.0) | |||||
| Postpartum Hemorrhage | N/A | N/A | 0.09 | 0.03 | |||||
| Yes | 85 (37) | 93 (44.9) | 99 (38.7) | 105 (48.8) | |||||
| No | 145 (63) | 114 (55.1) | 157 (61.3) | 110 (51.2) | |||||
| Placental abruption | N/A | N/A | – | 0.5 a | |||||
| No | 230 (100) | 207 (100) | 256 (100) | 214 (99.5) | |||||
| Yes | 0 (0) | 0 (0) | 0 (0) | 1 (0.5) | |||||
TOP Termination of pregnancy
aFischer’s Exact