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Immunohistochemical IgG staining (marker of BBB leakage; A and B) around single shank electrode in control (A) and PDA-PSB (B) groups. Scale bar in A and B is 100 μm. (C) is the normalized intensity values for IgG expression (histological samples, for control N=4. animal, N=8 sample; PDA-PSB N=4 animal, N=8 sample. Results were binned 10 μm from the electrode-tissue interface until 240 μm away, with 20 μm bin size. Data showed as mean ±SE; * indicates p<0.05.
