Comparison of the mRNA and protein levels of IL-37 between the CHD patients and HCs. (A) The IL-37 mRNA expression levels in PBMCs from AMI (n=30), UAP (n=31), and SAP patients (n=31), and HCs (n=46) were assessed by RT-PCR; the results are expressed as the means ± SDs. (B) Serum IL-37 levels in AMI (n=30), UAP (n=31), and SAP patients (n=31), and HCs (n=46) were measured by ELISA. Each symbol represents an individual CHD patient and HC. The horizontal lines indicate the median values. Differences between two groups were analysed by performing the Mann-Whitney U test for nonparametric data. *P<0.05; **P<0.01. IL-37, interleukin-37; CHD, coronary heart disease; PBMCs, peripheral blood mononuclear cells; AMI, acute myocardial infarction; UAP, unstable angina pectoris; SAP, stable angina pectoris; HC, healthy control; NS, not significant.