Table 1.
Summary of results for each vaccination failure patient.
| Patient No. | Age at disease (years) | Sex | Number of vaccine doses | Time from last vaccine dose to disease | No of sampling pointsa | Neutralization titer | IgM and IgG antibodies to WV antigen in sera | IgM antibodies to NS1 antigen in sera or CSF | IgM antibodies to NS1 antigen in sera alone |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 63 | Male | 4 | 2 years | 2 | 10, >160 | Positive | Positive | Negative |
| 2 | 67 | Male | 3 | 2 years | 1 | 640 | Positive | Positive | Positive |
| 3 | 39 | Male | 2 | 3 months | 1 | 80 | Positive | Positive | Positive |
| 4 | 21 | Male | 2 | 5 months | 1 | 40–80 | Positive | Positive | Positive |
| 5 | 6 | Male | 3 | 1 year | 1 | >160 | Positive | Positive | Positive |
| 6 | 67 | Female | 3 | Unknown | 2 | 640, 1280 | Positive | Positive | Positive |
| 7 | 55 | Female | 2 | 4 months | 1 | 160 | Positive | Positive | Positive |
| 8 | 52 | Female | 5 | 3 years | 1 | 5 | Positive | Negative | Negative |
| 9 | 68 | Male | 4 | 5 months | 1 | 80 | Positive | Positive | Positive |
| 10 | 64 | Male | 3 | 1 year | 2 | 20, 80 | Positive | Positive | Positive |
| 11 | 74 | Male | 4 | 3 years | 1 | 160 | Positive | Positive | Positive |
| 12 | 62 | Male | 4 | 3 years | 1 | n.d. | Positive | Negative | Negative |
| 13 | 72 | Male | 3 | 1 year | 1 | 320 | Positive | Positive | Positive |
| 14 | 76 | Male | 3 | 2 years | 1 | 80–160 | Positive | Negative | Negative |
| 14/14 | 11/14 | 10/14 |
aThree patients had more than one sample. Only one of the sampling points has been scored for each patient. See the Results section for more detailed explanation.