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. 2019 Dec 5;20:278. doi: 10.1186/s12931-019-1240-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Angiogenesis-related capillary remodelling in response to exercise training in skeletal muscle biopsies of COPD patients and SHS. a Transmission electron micrographs of capillaries from vastus lateralis biopsies of COPD patients and SHS. b Quantification of changes in relative volume and thickness of each capillary component following exercise training. RV: relative volume; T: thickness; Lum: lumen; EC: endothelium; BM: basement membrane; Pc: pericyte; Nucl: nucleus. Data are presented as means and individual values. Linear mixed-effect model: T: Time effect; GxT: Group x Time interaction. Post-hoc: Post-training different from Pre-training: *p < 0.05; ** p < 0.01. Scale bar: 1 μm