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. 2019 Dec 5;12:132. doi: 10.1186/s13045-019-0827-1

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — HNSCC cells exhibit differential response to saracatinib. a The effect of saracatinib on cell viability in different types of cancer cells determined by MTS assays on day 3 after treatment. b The IC50 of saracatinib in 5 different HNSCC cells determined by MTS assays on day 3 after treatment. c Comparison of saracatinib effect on cell viability in various HNSCC cell lines determined by MTS assays on day 3 after treatment. d The phosphorylation levels of Src in HNSCC cells determined by Western blotting. The representative result and quantitative data from three independent experiments were shown in the left and right panels, respectively. **p < 0.01