Table 3. Prevalence, prevalence ratio and analysis of factors associated with polypharmacy by Poisson regression model with robust variance. Diamantina, MG, Brazil, 2015 (n*= 210).
| Variable | % of polypharmacy | PR† | 95%CI‡ | p-value |
|---|---|---|---|---|
| Age (years) | ||||
| 18-45 | 11,4 | 1,00 | - | - |
| 46-60 | 31,6 | 2,56 | 1,25-5,21 | < 0,01 |
| 61-75 | 43,3 | 3,05 | 1,49-6,24 | < 0,01 |
| ≥76 | 46,1 | 2,73 | 1,29-5,78 | < 0,01 |
| Economic strata§ | ||||
| A | 100,0 | 1,00 | - | - |
| B | 20,0 | 0,17 | 0,09-0,31 | < 0,001 |
| C | 33,5 | 0,26 | 0,14-0,49 | < 0,001 |
| D and E | 47,7 | 0,33 | 0,17-0,65 | < 0,01 |
| Medication | ||||
| Way of acquisition | ||||
| Out-of-pocket | 34,9 | 1,00 | - | - |
| Out-of-pocket and SUS‖ | 82,1 | 1,44 | 1,07-1,94 | 0,01 |
| Diseases | ||||
| Hypertension | 24,8 | 1,00 | - | - |
| Diabetes and hypertension | 64,8 | 2,11 | 1,67-2,66 | < 0,001 |
| Comorbidities | ||||
| Stroke | ||||
| Yes | 61,8 | 1,64 | 1,22-2,21 | < 0,001 |
| No | 36,1 | 1,00 | - | - |
| Arrhythmia | ||||
| Yes | 58,3 | 1,56 | 1,07-2,27 | 0,02 |
| No | 36,7 | 1,00 | - | - |
| Hypercholesterolemia | ||||
| Yes | 69,6 | 1,43 | 1,02-2,01 | 0,03 |
| No | 36,3 | 1,00 | - | - |
| Coronary artery disease | ||||
| Yes | 72,7 | 2,26 | 1,37-3,72 | < 0,01 |
| No | 36,9 | 1,00 | - | - |
| Acess to medical assistance | ||||
| Hospital admission | ||||
| Yes | 65,9 | 1,73 | 1,41-2,11 | < 0,001 |
| No | 32,6 | 1,00 | - | - |
*
n = number of patients;
†
PR = Prevalence ratio;
‡
Confidence interval; Poisson regression, statistically significant p-value < 0.05; Only independent variables with p-value < 0.20 in the univariate analysis were included in the multivariate model;
§
Brazil criterion of economic classification;
‖
SUS = Brazilian Unified Health System