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. 2019 Nov 29;10:826. doi: 10.3389/fendo.2019.00826

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Copyright © 2019 Santini, Ceccarini, Pelosini, Giannetti, Ricco, Querci, Grossi, Saponati and Vitti.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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FT4/FT3 ratio in patients on L-T4 treatment (V1) and on L-T4+T3S (V5). The various groups are labeled according to the T4/T3S ratio of their treatment regimen: group A = 1.88, group B = 2.5, group C = 3.13. The 2 patients from group A and group B, who had to increase the T3S dose to 60 and 80 μg, respectively, are indicated as receiving a T4/T3S ratio = 1.25. The shaded area represents the 95% reference range for the FT4/FT3 ratio in the normal euthyroid population.