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. 2019 Oct 7;101(6):1312–1321. doi: 10.4269/ajtmh.18-0959

Figure 2.

Figure 2.

Evolution of the antibody titer against Mycobacterium ulcerans whole cell lysate (WCL) and small heat-shock protein 18 (Hsp18) measured in plasma from mice infected with M. ulcerans over time. A late onset of overall antibody response against an unspecific M. ulcerans WCL was noted in the bioluminescent M. ulcerans tail infection model. Antibody titers rose late, after 8 weeks, and plateaued at week 13 (A). No difference (P > 0.5) was observed in the antibody titer against small Hsp 18 and WCL (B). No statistical significance in antibody levels was seen between animals with severe, moderate, or no apparent pathology (P > 0.5; C).