Table 3.
Outcomes with significant changes from Year 1 to Year 5, for both study arms combined
| Odds ratio (reference = Year 1) | CI95% | P-value | |
|---|---|---|---|
| Infection prevalence | 0.36 | 0.28, 0.47 | < 0.0001 |
| Prevalence of heavy infections | 0.22 | 0.14, 0.36 | < 0.0001 |
| Wasting | 0.37 | 0.27, 0.50 | < 0.0001 |
| Stunting | 1.56 | 1.10, 2.21 | 0.02 |
| Elevated portal vein diameter | 0.13 | 0.07, 0.25 | < 0.0001 |
| Average change | CI95% | P-value | |
| VO2 (mL/kg/min) | −5.5 | −5.9, −5.2 | < 0.0001 |
| Pediatric quality of life inventory | |||
| Total score | 8 | 7, 9.1 | < 0.0001 |
| Physical | 6.2 | 4.8, 7.6 | < 0.0001 |
| Emotional | 14.8 | 13.3, 16.3 | < 0.0001 |
| Social | 2.9 | 1.5, 4.3 | < 0.0001 |
| School | 10.1 | 8.7,11.5 | < 0.0001 |
| Coefficient | CI95% | P-value | |
| Mean cohort-level infection intensity (epg) | −0.92 | −0.93, −0.91 | < 0.0001 |
epg = S. mansoni eggs per gram feces; VO2 max = maximal oxygen uptake as estimated by fitness testing.