Table 2.
Predictive Markers Associated with LADA Diagnosis
| Type 1a | LADAa | |||
|---|---|---|---|---|
| OR | 95% CI | OR | 95% CI | |
| Male | 1.99 | 0.58, 6.81 | 0.68 | 0.24, 1.90 |
| Age, years | 0.96 | 0.90, 1.03 | 0.95 | 0.90, 1.01 |
| Age at diagnosis, years | 0.97 | 0.90, 1.05 | 1.04 | 0.97, 1.12 |
| BMI, kg/m2 | 0.66 | 0.54, 0.81 | 0.86 | 0.73, 1.02 |
| HDL, mmol/L | 0.51 | 0.05, 5.02 | 3.17 | 0.46, 21.71 |
| Triglyceride, mmol/L | 1.12 | 0.86, 1.47 | 0.58 | 0.24, 1.43 |
| Fast plasma glucose, mmol/L | 1.42 | 1.19, 1.70 | 1.28 | 1.09, 1.50 |
| Fast C-peptide, ng/mL | 0.05 | 0.01, 0.24 | 0.30 | 0.11, 0.82 |
| UCPCR, nmol/mmol | 0.15 | 0.03, 0.92 | 0.29 | 0.09, 0.95 |
Notes: a Multinomial regression model was used for adjusting confounders. T2DM was the referent outcome and T1DM and LADA were compared with T2DM.
Abbreviations: T1DM, type 1 diabetes mellitus; T2DM, type 2 diabetes mellitus; LADA, latent autoimmune diabetes in adults; BMI, body mass index; HDL-C, high-density lipoprotein cholesterol; UCPR, urinary C-peptide creatinine ratio.