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. 2019 Dec 2;14:9483–9496. doi: 10.2147/IJN.S224160

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© 2019 Zhao et al.

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Tumor-targeting property of AsNPs at the cellular level.

Notes: C6 glioma cells and normal human microvascular endothelial cells (HMEC-1) were used in the experiment. (A) Representative dark-field images. Scale bar: 25 μm. (B) Representative confocal images. The cell membranes were stained with DiD (red color), while the cell nuclei were stained with DAPI (blue color). The bright spots represented AsNPs. Scale bar: 25 μm.

Abbreviations: AsNPs, PEG- and As1411-functionalized silver nanoparticles; μm, micrometer; DiD, 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindodicarbocyanine; DAPI, 4′,6-diamidino-2-phenylindole dihydrochloride.