Figure 1.
miR-509-5p is decreased and reversely correlated with PCNA expression in germ cells from infertile men with maturation arrest. (A-B) miR-509-5p level (A) and PCNA level (B) in the testes of normal controls (NC, n = 8) and infertile men with maturation arrest (MA, n = 12) were determined by qRT-PCR analysis. U6 snRNA and β-actin were used as internal controls, respectively. Each symbol represents the mean value from 3 replicates. P values are shown above. (C) The correlation of miR-509-5p level and PCNA level shown as in (A-B) was analyzed by the Pearson’s correlation analysis. r = −0.7139; P = 0.0004; n = 20.