Table 2.

SOFI questionnaire results by category and symptom. The data were averaged over all subjects as well as the 5 days in each study arm.

	BLFL				Non-BLFL				Mann–Whitney
	Mean	Standard deviation	Median	Range	Mean	Standard deviation	Median	Range	$z$-value	$P$-value
Lack of energy	2.58	2.28	2.00	—	2.97	2.30	2.50	—	$-0.973$	0.3306
Worn out	2.90	2.44	2.00	0 to 8	3.04	2.32	3.00	0 to 9	$-0.383$	0.7018
Spent	2.61	2.44	2.00	0 to 8	2.98	2.51	2.00	0 to 9	$-0.790$	0.4295
Drained	2.69	2.52	2.00	0 to 8	3.15	2.60	2.50	0 to 9	$-0.942$	0.3463
Overworked	2.10	2.16	2.00	0 to 8	2.71	2.77	2.00	0 to 8	$-0.821$	0.4116
Lack of motivation	2.44	1.59	2.00	—	3.02	1.85	2.00	—	$-1.411$	0.1583
Lack concern	4.75	2.88	4.00	1 to 8	5.85	2.78	8.00	1 to 8	$-1.780$	0.0751
Passive	1.79	2.15	1.00	0 to 8	2.42	2.70	1.00	0 to 8	$-0.880$	0.3790
Indifferent	1.61	2.08	1.00	0 to 8	1.88	2.55	0.50	0 to 8	$-0.062$	0.9505
Uninterested	1.62	2.26	1.00	0 to 9	1.92	2.69	2.50	0 to 8	$-0.138$	0.8903
Sleepiness	2.19	2.24	1.50	—	2.81	2.31	2.50	—	$-1.37$	0.1698
Falling asleep	2.35	2.46	2.00	0 to 8	2.71	2.54	2.00	0 to 8	$-0.735$	0.4625
Drowsy	1.65	2.50	0.00	0 to 8	2.56	2.63	5.00	0 to 9	$-1.901$	0.0573
Yawning	2.15	2.41	1.50	0 to 9	2.50	2.50	2.00	0 to 8	$-0.697$	0.4859
Sleepy	2.64	2.51	2.00	0 to 8	3.46	2.90	3.00	0 to 9	$-1.349$	0.1774
Physical exertion	0.43	0.74	0.00	—	0.39	0.67	0.00	—	0.290	0.7720
Palpitations	0.42	0.94	0.00	0 to 4	0.38	1.00	0.00	0 to 5	0.366	0.7146
Sweaty	0.75	1.34	0.00	0 to 5	0.63	1.34	0.00	0 to 7	0.048	0.9615
Out of breath	0.27	0.60	0.00	0 to 2	0.29	0.82	0.00	0 to 5	$-0.083$	0.9340
Breathing heavily	0.27	0.56	0.00	0 to 2	0.27	0.64	0.00	0 to 3	0.176	0.8603
Physical discomfort	0.85	0.89	0.50	—	1.29	1.35	1.00	—	$-1.587$	0.1125
Tense muscles	1.71	1.96	1.00	0 to 8	2.35	2.51	2.00	0 to 9	$-1.125$	0.2608
Numbness	0.40	0.75	0.00	0 to 3	0.48	1.09	0.00	0 to 6	$-0.100$	0.9203
Stiff joints	0.65	0.93	0.00	0 to 4	1.17	1.67	1.00	0 to 7	$-1.273$	0.2030
Aching	0.65	0.97	0.00	0 to 4	1.15	1.68	1.00	0 to 7	$-1.356$	0.1752
Overall general fatigue	1.75	1.26	1.42	—	2.10	1.41	1.72	—	$-1.34$	0.1807