Table 2.
Sustained Proliferative Signaling |
Evasion of Growth Suppressors |
Resisting Programmed Cell Death - apoptosis |
Induction of Vasculogenesis and Angiogenesis |
Overcoming Immune System Defenses |
Reprogramming Cellular Energetics |
Cellular Immortality |
Mobilization and Metastasis |
Create Tumor Microenvironment through Recruitment of Stromal Cells |