Skip to main content
. Author manuscript; available in PMC: 2020 May 20.
Published in final edited form as: Nature. 2019 Nov 20;576(7785):112–120. doi: 10.1038/s41586-019-1775-1

Extended Data Fig. 7 ∣. Driver gene nomination.

Extended Data Fig. 7 ∣

a. Local (gene-wise) dNdScv estimates by subtype (rows) and fraction (columns). Genes are sorted by Q-value and P-value. The Q-value is shown in color, whereas the P-value is indicated in light gray. The Q-value threshold of 0.05 is indicated by a horizontal red line. b. GISTIC significant amplification (red) and deletion (blue) plots in initial (left) and recurrent tumors (right). Chromosomal locations are ordered on the y-axis, Q-values are shown on the x-axis, and selected drivers are indicated by their chromosomal location on the right.