Reduce the burden of oncological therapy (REBOOT) Group B treatment schema. COM, cyclophosphamide (cytoxan), vincristine, methotrexate; COM3RA25D1, cyclophosphamide, vincristine, methotrexate, rituximab, doxorubicin (adriamycin), dexamethasone; COP, cyclophosphamide, vincristine, prednisone; dz, disease; HC, hydrocortisone; IT, intrathecal; MTX, methotrexate; R-CyM, rituximab, cytarabine, methotrexate.