Non-invasive risk assessment at DLBCL diagnosis by ctDNA. CI, confidence interval; ctDNA, circulating tumour DNA; DLBCL, diffuse large B-cell lymphoma; EFS, event-free survival; HR, hazard ratio; IPI, International Prognostic Index; TMTV, total metabolic tumour volume. From Kurtz, D.M. et al Circulating Tumor DNA Measurements As Early Outcome Predictors in Diffuse Large B-Cell Lymphoma. J Clin Oncol, 36, 2845–2853. Reprinted with permission. © 2018 American Society of Clinical Oncology. All rights reserved.